Autonomic hyperactivity, hand tremor, nausea, or vomiting are most commonly signs of withdrawal from which category of substances?

The signs of autonomic hyperactivity, hand tremor, nausea, and vomiting are indeed most commonly associated with withdrawal from sedative, hypnotic, or anxiolytic substances. These symptoms arise because these substances, which include medications such as benzodiazepines and barbiturates, act as central nervous system depressants. When a person who has been using these substances suddenly reduces or stops their intake, their body may react with a hyperactive state that contrasts sharply with the previous depressant effects.

Withdrawal from these substances can lead to a range of physical and psychological symptoms due to the body's attempt to rebalance itself after prolonged suppression of the central nervous system. The autonomic hyperactivity can manifest as increased heart rate, sweating, and elevated blood pressure. Hand tremors are a common physical sign, reflecting the body's stress response, while nausea and vomiting can occur due to the body's struggle to adapt to the absence of the substance it has become accustomed to.

In contrast, while withdrawal from stimulants can cause mood changes and fatigue, it typically does not include the autonomic symptoms mentioned. Opioid withdrawal presents differently, often involving muscle aches, increased pain sensitivity, and gastrointestinal disturbances but typically less nausea and autonomic hyperactivity than that